Biological Safety

Resources

American Biological Safety Association Risk Group Database

American Biological Safety Association Risk Group Database
Infectious agents are categorized in risk groups 1-4 based on their relative risk. Risk group classifications are used as part of a comprehensive biosafety risk assessment. The classification system takes multiple factors into consideration, including pathogenicity, virulence, mode of transmission, host range, and availability of treatment.

Biosafety in Microbiological and Biomedical Laboratories 5th ed. (CDC & NIH)

Biosafety in Microbiological and Biomedical Laboratories 5th ed. (CDC & NIH)
This biosafety manual describes the combinations of standard and special microbiological practices, safety equipment, and facilities constituting biosafety levels 1-4, which are recommended for work with a variety of infectious agents in various laboratory settings. The latest edition is augmented to cover decontamination and sterilization, biological toxins, and infectious agent summary statements.

California Department of Public Health Medical Waste Training Materials

California Department of Public Health Medical Waste Training Materials
This document contains training materials supplied to UCSB EH&S by environmental scientists from the Medical Waste Management Program at the California Department of Public Health. The training materials summarize California state requirements for medical waste containment, storage, and transport.

Canadian PSDS for Infectious Substances

Canadian PSDS for Infectious Substances
The Public Health Agency of Canada maintains a database of “Pathogen Safety Data Sheets” (PSDS) for infectious agents. Laboratory personnel are potentially exposed to much higher concentrations of human pathogens than the general public. The PSDS are organized to contain health hazard information that is relevant to the laboratory setting such as infectious dose, viability, handling, decontamination, spill procedures and reported lab-acquired infections.

Centers for Disease Control and Prevention – Emergency Needlestick Information

Centers for Disease Control and Prevention – Emergency Needlestick Information
This site contains updated U.S. Public Health Service guidelines for the management of occupational exposures to Hepatitis B, Hepatitis C, and HIV and recommendations for post exposure prophylaxis.

Centers for Disease Control and Prevention – Morbidity and Mortality Weekly Report

Centers for Disease Control and Prevention – Morbidity and Mortality Weekly Report
The report series is the CDC’s primary vehicle for scientific publication of timely, reliable, authoritative, accurate, objective, and useful public health information and recommendations. Readership predominately consists of physicians, nurses, public health practitioners, epidemiologists and other scientists, researchers, educators, and laboratorians.

Environmental Protection Agency-Registered Disinfectants

Environmental Protection Agency-Registered Disinfectants
Listings of EPA’s registered antimicrobial products effective against certain bloodborne/body fluid pathogens, Mycobacteria tuberculosis, human HIV-1 virus, Hepatitis B, Hepatitis C viruses, as well as products classified as sterilizers.

Guidelines for Disinfection and Sterilization in Healthcare Facilities, 2008 (CDC)

Guidelines for Disinfection and Sterilization in Healthcare Facilities, 2008 (CDC)
This publication presents recommendations on methods for cleaning, disinfection and sterilization for the healthcare environment that are entirely applicable to the laboratory environment. The guideline was updated to include the inactivation of antibiotic-resistant bacteria and emerging pathogens, and the toxicologic, environmental, and occupational concerns associated with disinfection and sterilization practices.

Lentiviral vector primer from the University of Cincinnati, March 2014

Lentiviral vector primer from the University of Cincinnati, March 2014
This primer contains valuable information for researchers who will begin using lentiviral vectors. The biosafety officer for UCSB has written permission from the biosafety officer for the University of Cincinnati to share their training material.

MCDB Autoclave Guidelines 5-23-14

MCDB Autoclave Guidelines 5-23-14

NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH)

NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH)
A document created in 1976 that outlines principles for the safe conduct of research employing recombinant DNA technology. The NIH Guidelines detail practices and procedures for the containment of various forms of recombinant DNA research, for the proper conduct of research involving genetically modified plants and animals, and for the safe conduct of human gene transfer research. As a living document, it is periodically revised to keep pace with scientific advances.

National Select Agent Registry List (CDC)

National Select Agent Registry List (CDC)
The National Select Agents Registry Program oversees the possession and use of biological agents and toxins that have the potential to pose a severe threat to public, animal or plant health, or to animal or plant products. The U.S. Departments of Health and Human Services and Agriculture have published final rules for the possession, use, and transfer of select agents and toxins (42 CFR Part 73, 7 CFR Part 331, and 9 CFR Part 121). On this website you may access the current list of select agents and read more about the increased oversight around their possession and use.

Use of ultraviolet lights in biosafety cabinets

World Health Organization Laboratory Biosafety Manual, third edition

World Health Organization Laboratory Biosafety Manual, third edition
This manual covers risk assessments, the safe use of recombinant DNA technology, and guidelines for the commissioning and certification of laboratories. This manual is also available in several different languages and those versions are accessible by a simple web search.