Biological Safety

Bloodborne Pathogens

Federal and state Bloodborne Pathogens Standards, OSHA 29 CFR 1910.1030 and Cal/OSHA CCR Title 8 Section 5193, are intended to mitigate occupational exposures to pathogens transmitted in human or primate blood or other potentially infectious materials (OPIM). The regulations specify that employers must implement an effective program to minimize exposure of employees to potential sources of bloodborne pathogens.

Scope of the Regulations with Regard to Laboratory Research

Principal Investigators with laboratory operations involving any reasonable, occupational risk of exposure to human or primate blood or bodily fluids must establish, implement and maintain a written exposure control plan that meets the requirements of OSHA 29 CFR 1910.1030 (c) and CCR Title 8 Section 5193 (c).

The Biological Use Authorization as the Bloodborne Pathogens Exposure Control Plan

Within the UC system, a biological use authorization (BUA) is required for work with human or primate blood or tissues. BUA applications document the safety protocols and appropriate barriers to prevent direct contact with human blood or OPIM for researchers. For BUAs involving work with human or primate blood or OPIM, the BBP ECP Addendum (link below) will be inserted within the BUA section for additional information by either the Principal Investigator or the Campus Biosafety Officer (BSO). The addendum will cover the remaining requirements that are not covered in the standard BUA and that are needed to comply with the regulations.

BUAs are renewed every three years. However, in order to comply with the bloodborne pathogens (BBP) regulations, this BUA must be updated by the Principal Investigator (PI) as necessary and annually with, at a minimum,

  1. BBP refresher training dates for all researchers on the project,
  2. Initials of researchers on the project to document their review of the safety protocols,
  3. Biosafety cabinet certification date(s).

Any updates and the annual review of the exposure control plan/BUA must be aknowledged and documented by the PI and the research group. Please file signatures pages with the Campus Biosafety Officer at or mail code 5132.

Training on the Bloodborne Pathogens Standards

Researchers must attend the in-person presentation once and thereafter fulfill the training requirement online or again in person.

For training dates, please see the general Training tab on the EH&S website.

If you have any questions, contact the Campus Biosafety Officer at or 805.893.8894.

BBP ECP Addendum
Full length BBP Exposure Control Plan Template
California Occupational Safety and Health Standard Title 8, section 5193
Hepatitis B Vaccination Declination
Occupational Safety and Health Administration Standard 1910.1030
Hepatitis B FAQs for the Public,” U.S. Department of Health & Human Services, Centers for Disease Control and Prevention, updated May 23, 2016.
Human Blood Cleanup Protocol