Biological Safety

Bloodborne Pathogens

Federal and state Bloodborne Pathogens Standards, OSHA 29 CFR 1910.1030 and Cal/OSHA CCR Title 8 Section 5193, are intended to mitigate occupational exposures to pathogens transmitted in human or primate blood or other potentially infectious materials (OPIM). The regulations specify that employers must implement an effective program to minimize exposure of employees to potential sources of bloodborne pathogens (BBP).

Scope of the Regulations with Regard to Laboratory Research

Principal Investigators with laboratory operations involving any reasonable, occupational risk of exposure to human or primate blood or bodily fluids must establish, implement and maintain a written exposure control plan that meets the requirements of OSHA 29 CFR 1910.1030 (c) and CCR Title 8 Section 5193 (c).

The Biological Use Authorization as the Bloodborne Pathogens Exposure Control Plan

Within the UC system, a biological use authorization (BUA) is required for work with human or primate blood or tissues. BUA applications document the safety protocols and appropriate barriers to prevent direct contact with human blood or OPIM for researchers. For BUAs involving work with human or primate blood or OPIM, the BUA will be supplemented with a section for hepatitis B vaccination/declination and annual acknowledgement of the exposure control plan. 

Cal/OSHA requires that exposure control plans are reviewed and acknowledged annually.
BUAs are to be updated with

  • BBP training dates within the last 12 months for group members,
  • Documented review of the safety protocols,
  • Biosafety cabinet certification date(s) as applicable.

Please file signatures pages with the biosafety officer at or mail code 5132.


Training on the BBP Standards

Training is required annually. The biosafety officer provides monthly in-person (videoconference) training on the regulations and their implementation at UCSB; dates and times are on the EH&S Training tab.
An online refresher unit is available through the UCSB Learning Center. Attendees of in-person presentations are automatically enrolled to access the refresher. The prerequisite is one in-person presentation.  

UCSB Bloodborne Pathogens Exposure Control Plan template
Signature pages for HBV and annual review
Hepatitis B FAQs for the Public, U.S. Department of Health & Human Services, Centers for Disease Control and Prevention
Human Blood Cleanup Protocol